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Volume 9, Number 7—July 2003

Synopsis

Disease Surveillance and the Academic, Clinical, and Public Health Communities

Robert W. Pinner*Comments to Author , Catherine A. Rebmann*, Anne Schuchat*, and James M. Hughes*
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA

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Table 2

Infectious causes and explanations for unexplained deaths and critical illnesses cases, 1995–1998, California, Oregon, Connecticut, and Minnesota (n=34)a,b

Syndrome Etiology (n) Tests (n)
Neurologic (n=15)
Neisseria meningitidis (4)
16S rDNA PCR (2), PCR (1), EIA IgM (1)a
Bartonella hensaelae (1)
PCR, IFA, IgG
Bartonella spp. (2)
IFA, IgG
Chlamydia pneumoniae (1)
MIF, IgG
Mycoplasma pneumoniae (1)
EIA, IgM/IgG
Cytomegalovirus (1)
EIA and IFA,IgG
Coxsackie B (1)
EIA,IgM, viral culture
Enterovirus (1)
EIA,IgM
Epstein-Barr virus (1)
IFA,IgG (VCA and EA)
Human herpes virus 6 (1)
IFA and EIA (IgM and IgG)
Mumps virus (1)
IFA IgM, IFA and EIA, IgG
Respiratory (n=13)
Chlamydia pneumoniae (2)
MIF IgG (2), IFA, IgM
Mycoplasma pneumoniae (4)
                    PCR (blood), EIA, IgM/IgG
Streptococcus pneumoniae (2)
16S rDNA PCR (pleural fluid)
Legionella spp. (1)
PCR (from lung)
Adenovirus (1)
EIA and IFA, IgG
Influenza B virus (1)
                    EIA and IFA, IgG
Influenza A virus (1)
EIA and IFA, IgM, EIA (IgG)
Human parainfluenza virus types 1 and 3 (1)
EIA and IFA, IgG
Cardiac (n=3)
Borrelia burgdorferi/Ehrlichia chaffeensis (1)
                    EIA/IFA flagella, IgG, Western Blot (IgG and IgM)
Enterovirus (1)
EIA IgM
Legionella spp. (1)
                    PCR (heart)
Multisystem (n=3) Neisseria meningitidis (1)
PCR (cerebrospinal fluid)
Adenovirus (1)
PCR (blood)
Enterovirus (1) IgM, EIA

a PCR, polymerase chain reaction; EIA, enzyme immunosorbent assay; IFA, indirect immunofluorescent assay; IG, immunoglobulin; MIF, microimmunofluorescence.

bReference 12.

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