Volume 9, Number 7—July 2003
Research
Acute Flaccid Paralysis and West Nile Virus Infection
James J. Sejvar*
, A. Arturo Leis†, Dobrivoje S. Stokic†, Jay A. Van Gerpen‡, Anthony A. Marfin*, Risa Webb§, Maryam B. Haddad*, Bruce C. Tierney*, Sally A. Slavinski§, Jo Lynn Polk†, Victor Dostrow†, Michael Winkelmann†, and Lyle R. Petersen*
, A. Arturo Leis†, Dobrivoje S. Stokic†, Jay A. Van Gerpen‡, Anthony A. Marfin*, Risa Webb§, Maryam B. Haddad*, Bruce C. Tierney*, Sally A. Slavinski§, Jo Lynn Polk†, Victor Dostrow†, Michael Winkelmann†, and Lyle R. Petersen*Table 1
Serologic results for West Nile virus (WNV)–specific antibodies in patients with acute flaccid paralysis associated with acute WNV infectiona
| IgM-capture enzyme immunoassay | Plaque reduction neutralization assay | ||||||
|---|---|---|---|---|---|---|---|
| Case |
Onset |
Collection |
Sample |
SLEV |
WNV |
SLEV |
WNV |
| 1 |
6/24 |
7/12 |
Serum |
3.5 |
22.3 |
320 |
5,120 |
| 2 |
7/12 |
7/16 |
Serum |
8.0 |
22.7 |
80 |
1,280 |
| 3 |
7/26 |
8/1 |
Serum |
2.79 |
24.9 |
<10 |
640 |
| 4 |
7/29 |
8/3 |
Serum |
1.1 |
14.1 |
<10 |
80 |
| 4 |
7/29 |
8/3 |
CSF |
3.3 |
39.2 |
||
| 4 |
7/29 |
8/13 |
Serum |
4.4 |
23.5 |
40 |
2,560 |
| 5 |
8/11 |
8/15 |
Serum |
2.02 |
|||
| 5 |
8/11 |
8/29 |
Serum |
3.4 |
25.7 |
||
| 6 |
8/13 |
8/16 |
CSF |
6.1 |
23.8 |
||
| 6 |
8/13 |
8/16 |
Serum |
1.0 |
5.7 |
<10 |
40 |
| 7 |
9/1 |
10/24 |
Serum |
2.8 |
10.6 |
10 |
320 |
| 7 | 9/1 | 9/6 | CSF | Not performed | 7.4 | ||
aIgM, immunoglobulin M; SLEV, Saint Louis encephalitis virus; CSF, cerebrospinal fluid.
