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Volume 27, Number 6—June 2021
Research

Increased Incidence of Antimicrobial-Resistant Nontyphoidal Salmonella Infections, United States, 2004–2016

Felicita MedallaComments to Author , Weidong Gu, Cindy R. Friedman, Michael Judd, Jason Folster, Patricia M. Griffin, and Robert M. Hoekstra
Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Figure 3

Estimated changes in the incidence of resistant culture-confirmed nontyphoidal Salmonella infections, by serotype, resistance category, and geographic region, United States, 2015–2016 versus 2010–2014. Estimated changes in resistance incidence (mean and 95% credible intervals of the posterior differences per 100,000 persons/year) were derived using Bayesian hierarchical models. Amp-only, Cef/Amp, and Cipro are mutually exclusive categories of clinically important resistance: Amp-only, resistant to ampicillin but susceptible to ceftriaxone and ciprofloxacin; Cef/Amp, resistant to ceftriaxone and ampicillin; Cipro, nonsusceptible to ciprofloxacin but susceptible to ceftriaxone. Isolates in each category might have resistance to other agents. Multidrug resistance (MDR) was defined as resistance to >3 classes of antimicrobial agents. The “other” category comprised serotypes other than Enteritidis, Typhimurium, Newport, I 4,[5],12:i:-, and Heidelberg. US Census regions were used to define 4 geographic regions (A, all regions; M, Midwest; N, Northeast; S, South; W, West). MDR, multidrug resistant; NTS, all nontyphoidal Salmonella serotypes.

Figure 3. Estimated changes in the incidence of resistant culture-confirmed nontyphoidal Salmonella infections, by serotype, resistance category, and geographic region, United States, 2015–2016 versus 2010–2014. Estimated changes in resistance incidence (mean and 95% credible intervals of the posterior differences per 100,000 persons/year) were derived using Bayesian hierarchical models. Amp-only, Cef/Amp, and Cipro are mutually exclusive categories of clinically important resistance: Amp-only, resistant to ampicillin but susceptible to ceftriaxone and ciprofloxacin; Cef/Amp, resistant to ceftriaxone and ampicillin; Cipro, nonsusceptible to ciprofloxacin but susceptible to ceftriaxone. Isolates in each category might have resistance to other agents. Multidrug resistance (MDR) was defined as resistance to >3 classes of antimicrobial agents. The “other” category comprised serotypes other than Enteritidis, Typhimurium, Newport, I 4,[5],12:i:-, and Heidelberg. US Census regions were used to define 4 geographic regions (A, all regions; M, Midwest; N, Northeast; S, South; W, West). MDR, multidrug resistant; NTS, all nontyphoidal Salmonella serotypes.

Main Article

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