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Volume 30, Number 11—November 2024
Research

Quantitative SARS-CoV-2 Spike Receptor-Binding Domain and Neutralizing Antibody Titers in Previously Infected Persons, United States, January 2021–February 2022

Anna BratcherComments to Author , Szu-Yu Kao, Kelly Chun, Christos J. Petropoulos, Adi V. Gundlapalli, Jefferson Jones1, and Kristie E.N. Clarke1
Author affiliation: Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA (A. Bratcher); Alan Shawn Feinstein College of Education, University of Rhode Island, Kingston, Rhode Island, USA (S.-Y. Kao); Labcorp Esoterix, Calabasas, California, USA (K. Chun); Labcorp-Monogram Biosciences, South San Francisco, California, USA (C.J. Petropoulos); Centers for Disease Control and Prevention, Atlanta (A.V. Gundlapalli, J. Jones, K.E.N. Clarke)

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Figure 4

Violin plots of anti-RBD IgG and NT50 titer results by age group in a study of quantitative SARS-CoV-2 spike RBD and neutralizing antibody titers in previously infected persons, United States, January 2021–February 2022. A) Anti-RBD, n = 30,967; B) NT50, n = 744. Anti-RBD measured by Cov2Quant IgG (LabCorp, https://www.labcorp.com) and NT50 measured by PhenoSense SARS-CoV-2 Neutralizing Antibody Assay (Monogram Biosciences, https://monogrambio.labcorp.com). Horizontal lines in plots indicate first quantile, median, and third quantile; black dots indicates means. BAU, binding antibody units; NT50, 50% neutralization titer; RBD, receptor-binding domain.

Figure 4. Violin plots of anti-RBD IgG and NT50 titer results by age group in a study of quantitative SARS-CoV-2 spike RBD and neutralizing antibody titers in previously infected persons, United States, January 2021–February 2022. A) Anti-RBD, n = 30,967; B) NT50, n = 744. Anti-RBD measured by Cov2Quant IgG (LabCorp, https://www.labcorp.com) and NT50 measured by PhenoSense SARS-CoV-2 Neutralizing Antibody Assay (Monogram Biosciences, https://monogrambio.labcorp.com). Horizontal lines in plots indicate first quantile, median, and third quantile; black dots indicates means. BAU, binding antibody units; NT50, 50% neutralization titer; RBD, receptor-binding domain.

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1These co-senior authors contributed equally to this article.

Page created: September 30, 2024
Page updated: October 22, 2024
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