Volume 30, Number 12—December 2024
Research
Novel Mastadenovirus Infection as Cause of Pneumonia in Imported Black-and-White Colobuses (Colobus guereza), Thailand
Figure 10

Figure 10. Transmission electron microscopy of formalin-fixed paraffin embedded lung section of case 1 in an investigation of novel mastadenovirus infection causing pneumonia in imported black-and-white colobuses (Colobus guereza), Thailand. A) Destructed bronchial epithelial cell showing degenerated plasma membrane and a large cytoplasmic vacuole containing electron-dense particles (inset area of interest at 100× magnification). N indicates nuclear membrane. Scale bar indicates 200 nm. B) Random viral particles distributed in cytosol; viral particles are seen near ruptured nuclear (N) membrane (inset area of interest at 100× magnification). Scale bar indicates 100 nm. C) Mature icosahedral electron-dense viral particles in the cytosol. Black arrows indicate plasma membrane. Scale bar indicates 100 nm. D) A vacuole containing electron-lucent particle and a free-living electron-dense particle in the cytosol. Scale bar indicates 100 nm.