Volume 7, Number 7—June 2001
THEME ISSUE
International Conference on Emerging Infectious Diseases 2000
Conference Presentations
Antibacterial Household Products: Cause for Concern
Table 4
Mutations in InhA confer triclosan resistance in Mycobacterium smegmatis (9)
InhA | Relative MIC (in 7H9 medium) |
|||
---|---|---|---|---|
Strain | Selected ona | mutation | TRC | INH |
mc2155 (wt) | — | None | 1.0 | 1.0 |
MT 1 | TRC | M161V | 6.3 | 8.5 |
MT 9 | TRC | M103T | 6.3 | 1.2 |
MT 17 | TRC | A124V | 5.8 | 2.0 |
mc2651 | INH | S94A | 6.3 | 22.0 |
mc2155 (p::inhA) | — | None | 6.3 | >64 |
aTRC, triclosan; INH, isoniazid