Volume 10, Number 4—April 2004
Synopsis
Pediatric Influenza Prevention and Control
Nicola Principi*
and Susanna Esposito*
and Susanna Esposito*Table 3
Effectiveness of influenza vaccine among household contacts of children receiving influenza vaccine and unvaccinated controlsa
| Event | Household contacts of vaccinated children (n = 728)b | Household contacts of unvaccinated controls (n = 370)b | Vaccine effectiveness, %c | p value |
|---|---|---|---|---|
| No. of respiratory tract infections |
3.03 ± 1.68 |
4.27 ± 1.68 |
30 |
0.0005 |
| No. of medical visits because of respiratory illness |
2.18 ± 1.37 |
3.16 ± 1.77 |
32 |
0.002 |
| Loss of maternal work, days |
3.22 ± 1.86 |
4.78 ± 2.34 |
33 |
0.001 |
| Loss of paternal work, days |
0.56 ± 0.46 |
0.98 ± 2.24 |
43 |
0.001 |
| Help at home to care for ill children, days | 0.57 ± 0.37 | 3.22 ± 2.24 | 83 | <0.0001 |
aModified from S. Esposito et al. (39).
bMean values ± standard deviation.
cVaccine effectiveness: 1 minus attack rate (defined as rate of illness divided by the total population) among household contacts of vaccinated children divided by attack rate among household contacts of controls.
