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Volume 10, Number 5—May 2004

Research

Enzyme-Linked Immunosorbent Assay and Serologic Responses to Pneumocystis jiroveci

Kieran R. Daly*Comments to Author , Judy Koch*, Linda Levin*, and Peter D. Walzer*
Author affiliations: *University of Cincinnati College of Medicine, Cincinnati, Ohio, USA; ‡Veterans Affairs Medical Center, Cincinnati, Ohio, USA

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Table 1

Geometric mean values and 95% CI of ELISA by blood donor, PCP-positive, PCP-negative, and HIV status for each antigena

ELISA Antigen Blood donor, n = 95 (95% CI) PCP+, n = 33 (95% CI) PCP–, n = 66 (95% CI) HIV+ (PCP+, PCP–), n = 94 (95% CI)
1 (n = 189)
A
1.2 (0.8 to 1.8)
6.8 (4.1 to 11.3)
6.0 (4.6 to 7.7)
6.2 (4.9 to 7.9)
B
1.0 (0.7 to 1.4)
3.7 (2.4 to 5.8)
2.9 (2.3 to 3.6)
3.2 (2.5 to 3.9)
C
2.0 (1.2 to 3.1)
13.0 (7.9 to 21.4)
7.5 (6.0 to 9.3)
9.1 (7.3 to 11.4)
2 (n = 189)
A
9.0 (6.3 to 12.7)
31.2 (22.0 to 44.2)
28.9 (21.2 to 39.5)
29.7 (23.6 to 37.4)
B
4.2 (2.7 to 6.6)
16.2 (11.5 to 22.7)
15.0 (11.9 to 18.9)
15.4 (12.8 to 18.6)
C
21.4 (15.0 to 30.7)
57.8 (48.1 to 69.3)
39.1 (31.7 to 48.2)
44.9 (38.5 to 52.2)
3 (n = 189) A
18.6 (10.5 to 32.9)
73.5 (53.0 to 102.1)
73.8 (54.1 to 100.7)
73.7 (58.6 to 92.7)
B
8.2 (4.0 to 16.6)
102.6 (73.0 to 144.2)
103.8 (83.0 to 129.7)
103.4 (86.1 to 124.2)
C 22.1 (12.6 to 38.6) 120.1 (99.8 to 144.5) 81.2 (66.7 to 98.9) 93.2 (80.5 to 107.9)

aCI, confidence interval; ELISA, enzyme-linked immunosorbent assay; PCP, Pneumocystis pneumonia.

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