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Volume 10, Number 5—May 2004

Research

Multidrug-resistant Tuberculosis in Central Asia

Helen Suzanne Cox*Comments to Author , Juan Daniel Orozco*, Roy Male*, Sabine Ruesch-Gerdes†, Dennis Falzon*, Ian Small*, Darebay Doshetov‡, Yared Kebede§, and Mohammed Aziz¶
Author affiliations: *Médecins Sans Frontières Aral Sea Area Programme, Uzbekistan and Turkmenistan, Tashkent, Uzbekistan; †National Reference Centre for Mycobacteria, Borstel, Germany; ‡Ministry of Health, Nukus, Karakalpakstan, Uzbekistan; §Médecins Sans Frontières, Amsterdam, the Netherlands; ¶World Health Organization, Geneva, Switzerland

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Table 5

Factors associated with MDR-TB in univariate and multivariable logistic regression analysisa

Odds ratios (95% confidence limits) Univariate analysis Logistic regression
Previous TB treatment 4.5 (2.6 to 8.0) 5.1 (2.8 to 9.3)
Region (Karakalpakstan) 3.0 (1.8 to 5.1) 3.6 (2.0 to 6.4)
Female gender 1.3 (0.8 to 2.2) 2.0 (1.1 to 3.7)
Unemployment 2.3 (1.1 to 5.1) 2.1 (0.9 to 4.8)
Previous imprisonment 1.7 (0.9 to 3.0) 1.3 (0.6 to 2.8)
Alcohol use 0.9 (0.4 to 2.3) 0.7 (0.3 to 1.9)

aMDR-TB, multidrug-resistant tuberculosis.

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