Volume 10, Number 6—June 2004
Research
Bovine Spongiform Encephalopathy Infectivity in Greater Kudu (Tragelaphus strepsiceros)
Andrew A. Cunningham*
, James K. Kirkwood*1, Michael Dawson†2, Yvonne I. Spencer†, Robert B. Green†, and Gerald A.H. Wells†
, James K. Kirkwood*1, Michael Dawson†2, Yvonne I. Spencer†, Robert B. Green†, and Gerald A.H. Wells†Table 3
Details of spongiform encephalopathy–positive greater kudu used for mouse inoculation studies
| Kudu Ref. | Age at death (mo.) | Sex | Brief history | Basis of diagnosis |
|---|---|---|---|---|
| A664 |
30 |
F |
Born at London Zoo. Died after progressive neurologic disease of approximately 72 hours. Examined postmortem on the same day. |
Histopathologic examination of brain and experimental transmission to mice. |
| A666 |
37 |
M |
Born at London Zoo. Killed after progressive neurologic disease of approximately 24 hours. Examined postmortem on the same day. |
Histopathologic, SAF, and PrPsc immunocytochemical examinations of the brain and spinal cord.a |
| A1221 |
18 |
M |
Born at London Zoo. Killed for management reasons as a clinically healthy animal and immediately examined postmortem. |
Histopathologic, SAF, and PrPsc immunocytochemical examinations of the brain and spinal cord. |
| A1212 | 39 | F | Born in Britain, moved to London Zoo at 12 months of age. Killed following progressive neurologic disease lasting approximately 1 month and immediately examined postmortem. | Histopathologic and SAF examinations of the brain. |
aSAF, scrapie-associated fibrils; PrPSc, transmissible spongiform encephalopathy-disease specific form of the PrP protein.
