Emerging Infectious Disease ISSN: 1080-6059

Fluoroquinolone and Other Antimicrobial Resistance in Invasive Pneumococci, Hong Kong, 1995–2001

Pak-Leung Ho*

, Tak-Lun Que†, Susan S. Chiu*, Raymond W. H. Yung†, Tak-Keung Ng§, Dominic N. C. Tsang¶, Wing-Hong Seto*, and Yu-Lung Lau*

Author affiliations: *Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region (SAR), China; †Tuen Mun Hospital, Hong Kong SAR, China; ‡Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, China; §Princess Margaret Hospital, Hong Kong, SAR, China; ¶Queen Elizabeth Hospital, Hong Kong SAR, China

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Figure 2

HinfI fingerprints of the pbp genes. A) pbp2b profiles. Lanes 1, marker; 2, Spain23F-1 clone (SP264, ATCC 700669); 3, a ciprofloxacin-resistant, levofloxacin-susceptible strain S1D3; 4, Spain6B clone (GM17, ATCC 700670); lane 5−14, 10 isolates of levofloxacin_resistant pneumococci (S3F7, S2H9, S1B7, S1B9, S1D5, S2D6, S1D2, S2F3, 186G1, and 216D2 respectively); B) pbp2x profiles. The lanes were arranged in the same sequence as in (A).

Figure 2. HinfI fingerprints of the pbp genes. A) pbp2b profiles. Lanes 1, marker; 2, Spain^23F-1 clone (SP264, ATCC 700669); 3, a ciprofloxacin-resistant, levofloxacin-susceptible strain S1D3; 4, Spain^6B clone (GM17, ATCC 700670); lane 5−14, 10 isolates of levofloxacin_resistant pneumococci (S3F7, S2H9, S1B7, S1B9, S1D5, S2D6, S1D2, S2F3, 186G1, and 216D2 respectively); B) pbp2x profiles. The lanes were arranged in the same sequence as in (A).

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