Figure 2. HinfI fingerprints of the pbp genes. A) pbp2b profiles. Lanes 1, marker; 2, Spain23F-1 clone (SP264, ATCC 700669); 3, a ciprofloxacin-resistant, levofloxacin-susceptible strain S1D3; 4, Spain6B clone (GM17, ATCC 700670); lane 5−14, 10 isolates of levofloxacin_resistant pneumococci (S3F7, S2H9, S1B7, S1B9, S1D5, S2D6, S1D2, S2F3, 186G1, and 216D2 respectively); B) pbp2x profiles. The lanes were arranged in the same sequence as in (A).