Skip directly to search Skip directly to A to Z list Skip directly to site content
CDC Home

Volume 10, Number 8—August 2004

Research

Long-Term Prognosis for Clinical West Nile Virus Infection

Anne Labowitz Klee*, Beth Maldin*, Barbara Edwin*, Iqbal Poshni*, Farzad Mostashari*, Annie Fine*, Marcelle Layton*, and Denis Nash*†1Comments to Author 
Author affiliations: *New York City Department of Health, New York City, New York, USA; †Centers for Disease Control and Prevention, Atlanta, Georgia, USA; 1Current affiliation: New York Academy of Medicine, New York, New York, USA

Main Article

Table 3

Prevalence of signs and symptoms at intervals of follow-up in patients with clinical West Nile virus infection, New York City, 1999

Sign or symptom Before illness onseta (baseline), n/N (%) Interview 1 (6 months), n/N (%) Interview 2 (12 months), n/N (%) Interview 3 (18 months), n/N (%) p value for 12 months vs. baselineb
Physical sequelae
Difficulty walking 7/35 (20.0) 30/38 (78.9) 17/35 (48.6) 15/36 (41.6) 0.002
Muscle weakness 4/35 (11.5) 25/38 (65.8) 15/34 (44.1) 20/36 (55.5) < 0.001
Fatigue 12/35 (34.3) 20/37 (54.1) 22/33 (66.7) 23/36 (63.8) 0.002
Insomnia 7/35 (20.0) 17/38 (44.7) 16/34 (47.1) 17/36 (47.2) 0.007
Muscle pain 12/35 (34.3) 14/37 (37.8) 19/34 (55.9) 14/36 (38.8) 0.035
Headache 9/35 (25.7) 13/37 (35.1) 15/34 (44.1) 13/36 (36.1) 0.014
Joint pain 7/35 (20.0) 12/38 (31.6) 11/34 (32.3) 11/36 (30.6) 0.157
Cognitive symptoms
Memory loss 7/35 (20.0) 21/38 (55.3) 17/34 (50.0) 16/36 (44.5) 0.002
Loss of concentration 3/35 (8.6) 16/37 (42.2) 14/34 (41.2) 12/36 (33.3) < 0.001
Depressed 5/35 (14.3) 15/38 (39.5) 13/34 (38.2) 16/36 (44.4) 0.005
Irritable 8/35 (22.9) 14/38 (36.8) 14/34 (41.2) 14/36 (38.9) 0.008
Lightheaded 4/35 (11.5) 13/38 (34.2) 17/33 (51.5) 13/35 (37.1) < 0.001
Confusion 2/35 (5.7) 17/38 (44.8) 9/34 (26.5) 11/36 (30.6) 0.008
Functional sequelae
Shopping 4/33 (12.1) 17/36 (47.2) 14/33 (42.4) 14/35 (40.0) 0.002
Meal preparation 2/32 (6.3) 22/31 (71.0) 12/32 (37.5) 12/34 (35.3) < 0.001
Laundry 1/25 (4.0) 14/29 (48.3) 10/25 (40.0) 10/33 (30.3) 0.003
Light housekeeping 1/28 (3.6) 19/35 (54.3) 12/28 (42.9) 12/35 (34.3) < 0.001
Heavy chores 5/30 (11.9) 19/33 (57.6) 19/30 (63.3) 19/34 (55.9) 0.003
Transportation 3/29 (10.3) 23/37 (62.2) 10/28 (35.7) 14/36 (38.9) 0.008

aAssessed by recall at the 12-month follow-up interview.
bBased on McNemar’s test for agreement in a matched analysis.

Main Article

Top of Page

USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO