Figure 2. Phylogenetic tree showing the relationship between human parechovirus (HPeV)-3 Canadian isolates no. 81235, 81554, and 82853 and other HPeV-3 (A628-99, GenBank accession no. AB112484; A354-99, no. AB112483; A317-99, no. AB112482; A308-99, no. AB084913), HPeV-2 (Williamson, no. AJ005695; Connecticut, no. AF055846) and HPeV-1 (Harris, no. S45208; A10987-00, no. AB112487; A942-99, no. AB112486; A1086-99, no. AB112485) strains based on amino acid differences in capsid proteins (VP0-VP3-VP1 region). The tree was constructed by using the neighbor-joining method. Numbers represent the frequency of occurrence of nodes in 500 bootstrap replicas.