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Volume 11, Number 4—April 2005

Research

Experimental Infection of Prairie Dogs with Monkeypox Virus

Shu-Yuan Xiao*, Elena Sbrana*, Douglas M. Watts*, Marina Siirin*, Amelia P.A. Travassos da Rosa*, and Robert B. Tesh*Comments to Author 
Author affiliations: *University of Texas Medical Branch, Galveston, Texas, USA

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Table 2

Monkeypox virus titers in selected tissues of experimentally infected prairie dogs at death

Route of infection Animal no. Virus titer (log10 PFU/g of tissue)*
Liver Spleen Kidney Lung Heart Brain
Intraperitoneal MPX-1 8.1 7.2 4.3 6.7 0 0
MPX-3 7.6 7.4 5.4 6.8 3.5 3.6
MPX-4 7.7 8.4 5.4 7.1 5.5 NT
Intranasal MPX-5 0 0 0 0 0 NT
MPX-6 0 0 0 0 0 4.7
MPX-7 0 0 0 0 0 0
MPX-8 0 0 0 0 0 NT
MPX-9 3.0 2.4 2.4 8.0 4.5 0

*0, <0.7 (<100.7); NT, not tested.

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