Volume 11, Number 6—June 2005
Letter
Measuring Impact of Antimicrobial Resistance
Mary-Claire Roghmann*
, Douglas D. Bradham†, Min Zhan*, Scott K. Fridkin‡, and Trish M. Perl§
, Douglas D. Bradham†, Min Zhan*, Scott K. Fridkin‡, and Trish M. Perl§Table
Description of 187 adult patients with central vascular catheter-associated bloodstream infections with Staphylococcus aureus or Enterococcus faecium attributable to the intensive care unit*
| Characteristics | S. aureus (n = 109) | E. faecium (n = 78) | p value |
|---|---|---|---|
| Patient demographics | |||
| Male (%) | 74 | 56 | 0.02 |
| Mean age, y (SD) | 58 (17) | 56 (16) | 0.32 |
| Type of ICU | <0.01 | ||
| Cardiac (%) | 20 | 10 | |
| Cardiothoracic surgery (%) | 6 | 6 | |
| Medical (%) | 20 | 40 | |
| Neurologic/neurosurgical (%) | 6 | 0 | |
| Surgical (%) | 20 | 37 | |
| Trauma (%) | 28 | 6 | |
| Severity of illness | |||
| Mean APACHE II score at ICU admission (SD) | 19 (8) | 21 (9) | 0.12 |
| Mean APACHE II score within 7 days of BSI (SD) | 17 (8) | 20 (8) | 0.05 |
| Resistant infections (%) | 50 | 69 | 0.01 |
| In-hospital death rate (%) | 34 | 54 | <0.01 |
*SD, standard deviation; ICU, intensive care unit.
