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Volume 12, Number 6—June 2006

Research

Human Streptococcus suis Outbreak, Sichuan, China

Hongjie Yu*1, Huaiqi Jing†1, Zhihai Chen‡1, Han Zheng†, Xiaoping Zhu§, Hua Wang¶, Shiwen Wang*, Lunguang Liu§, Rongqiang Zu*, Longze Luo§, Nijuan Xiang*, Honglu Liu§, Xuecheng Liu§, Yuelong Shu*, Shui Shan Lee#, Shuk Kwan Chuang**, Yu Wang*, Jianguo Xu†, Weizhong Yang*Comments to Author , and the Streptococcus suis study groups
Author affiliations: *Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China; †State Key Laboratory for Infectious Disease Prevention and Control (ICDC), Beijing, China; ‡Beijing Ditan Hospital, Beijing, People's Republic of China; §Sichuan Center for Disease Control and Prevention, Sichuan, People's Republic of China; ¶Jiangsu Center for Disease Control and Prevention, Nanjing, People's Republic of China; #The Chinese University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China; **Centre for Health Protection, Hong Kong Special Administrative Region, People's Republic of China

Main Article

Table 2

Clinical symptoms and case-fatality ratio of 215 Streptococcus suis patients in Sichuan Province, China, 2005*

Clinical symptom Probable
Confirmed
Total
No. (%) No. deaths (case-fatality %) No. (%) No. deaths (case-fatality %) No. (%) No. deaths (case-fatality %)
Sepsis 45 (30) 0 7 (11) 0 52 (24) 0
Meningitis 69 (46) 1 (1) 33 (50) 0 102 (48) 1 (1)
STSS 35 (24) 23 (66) 26 (39) 15 (58) 61 (28) 38 (62)
Total 149 (100) 24 (16) 66 (100) 15 (23) 215 (100) 39 (18)

*Streptococcal toxic shock syndrome (STSS) is defined according to the 1996 criteria established by the Centers for Disease Control and Prevention, Atlanta, GA, USA, which include hypotension (systolic blood pressure <90 mm Hg for adults) and multiorgan involvement characterized by >2 of the following: renal impairment, coagulopathy, liver involvement, acute respiratory distress syndrome, generalized erythematous macular rash that may desquamate, soft-tissue necrosis, including necrotizing fasciitis or myositis, or gangrene. Difference in case-fatality ratio between STSS and other clinical symptoms p<0.001 by χ2 test.

Main Article

1These authors contributed equally to this article.

2Members of the Chinese Center for Disease Control and Prevention Streptococcus suis study group are Wenjun Zhong, Ling Meng, Yongjun Gao, Huamao Du, Changyu Ye, Zhigang Cui, Shouyin Zhang, and Dong Jin. Members of the Sichuan Center for Disease Control and Prevention Streptococcus suis study group are Li Liu, Heng Yuan, Bin Ouyang, Qiang Lv, Yan Huang, Ting Huang, Xingyu Zhou, Liao Feng, and Qidi Pang.

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