Volume 12, Number 6—June 2006
Research
Norwalk Virus–specific Binding to Oyster Digestive Tissues
Françoise S. Le Guyader*
, Fabienne Loisy*, Robert L. Atmar†, Anne M. Hutson†, Mary K. Estes†, Nathalie Ruvoën-Clouet‡§¶, Monique Pommepuy*, and Jacques Le Pendu§¶
, Fabienne Loisy*, Robert L. Atmar†, Anne M. Hutson†, Mary K. Estes†, Nathalie Ruvoën-Clouet‡§¶, Monique Pommepuy*, and Jacques Le Pendu§¶Table 1
Inhibition of binding of Norwalk viruslike particles (VLPs) to oyster digestive tissues by saliva
| Saliva | No. samples tested | VLP binding* |
|---|---|---|
| A | 14 | – |
| O | 18 | + |
| B | 4 | +++ |
| Nonsecretor | 5 | +++ |
| Control | 5 | +++ |
*After incubation with saliva, no (–), weak (+), or strong (+++) VLP binding to oyster digestive tissues was observed. For controls, VLPs were applied to shellfish tissues in phosphate-buffered saline/1% bovine serum albumin instead of a saliva sample diluted in the same buffer.
