Figure 5. Immunohistochemical detection of Rickettsia africae in the inoculation eschar of a patient with African tick-bite fever. Note the location of the bacteria in the endothelial and inflammatory cells of a blood vessel in the dermis (arrow) (monoclonal rabbit anti-R. africae antibody used at a dilution of 1:1,000 and hematoxylin counterstain; original magnification ×250).
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