Treatment outcome definitions for multidrug-resistant tuberculosis (MDRTB) patients (14)
||Completed treatment according to country protocol and been consistently culture-negative (>5 results) for final 12 mo of treatment. If only 1 positive culture is reported during that time with no concomitant clinical evidence of deterioration, patient may still be considered cured, provided that positive culture is followed by >3 consecutive negative cultures taken >30 d apart.
||Completed treatment according to country protocol but does not meet definition for cure or treatment failure because of lack of bacteriologic results (i.e., <5 cultures were performed in the final 12 mo of therapy).
||Died for any reason during the course of MDRTB treatment.
||Treatment was interrupted for >2 consecutive months for any reason.
||>2 of 5 cultures recorded in the final 12 mo are positive or if any of the final 3 cultures is positive. Treatment will also be considered to have failed if a clinical decision has been made to terminate treatment early due to poor response or adverse events.
||Transferred to another reporting and recording unit and the treatment outcome is unknown.