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Volume 13, Number 10—October 2007
THEME ISSUE
Global Poverty and Human Development

Research

Cost-effectiveness of Algorithms for Confirmation Test of Human African Trypanosomiasis

Pascal Lutumba*†, Filip Meheus‡, Jo Robays†, Constantin Miaka*, Victor Kande*, Philippe Büscher†, Bruno Dujardin§, and Marleen Boelaert†Comments to Author 
Author affiliations: *Programmed National de Lutte contre la Trypanosomiase Humaine Africaine, Kinshasa, Democratic Republic of Congo; †Institute of Tropical Medicine, Antwerp, Belgium; ‡Royal Tropical Institute, Amsterdam, the Netherlands; §Ecole de Santé Publique, Université Libre de Bruxelles, Brussels, Belgium;

Main Article

Table 1

Screening algorithms for human African trypanosomiasis*

Label Algorithm Abbreviation
Algorithm 1 
or standard Lymph node puncture, fresh blood examination, and thick blood film LNP-FBE-TBF
Algorithm 2 Lymph node puncture and capillary tube centrifugation LNP-CTC
Algorithm 3 Lymph node puncture, CATT titration, capillary tube centrifugation, and mini-anion exchange centrifugation technique LNP-CATT titration-CTC-mAECT
Algorithm 4 Lymph node puncture, capillary tube centrifugation, and mini-anion exchange technique LNP-CTC-mAECT
Algorithm 5 Lymph node puncture, thick blood film, capillary tube centrifugation, and mini-anion exchange technique LNP-TBF-CTC-mAECT
Algorithm 6 Lymph node puncture, capillary tube centrifugation, and CATT titration LNP-CTC-CATT titration
Algorithm 7 Lymph node puncture, thick blood film, capillary tube centrifugation, mini-anion exchange technique, and CATT titration LNP-TBF-CTC-mAECT-CATT titration

*CATT, card agglutination test for trypanosomiasis; CATT titration, CATT titration at end-titer 8.

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