Genetic Diversity among Clonal Lineages within Escherichia coli O157:H7 Stepwise Evolutionary Model
Peter C.H. Feng* , Steven R. Monday*, David W. Lacher†, Lesley Allison‡, Anja Siitonen§, Christine Keys*, Marjut Eklund§, Hideki Nagano¶, Helge Karch#, James Keen**, and Thomas S. Whittam†
Author affiliations: *Food and Drug Administration, College Park, Maryland, USA; †Michigan State University, East Lansing, Michigan, USA; ‡Western General Hospital, Edinburgh, Scotland; §National Public Health Institute, Helsinki, Finland; ¶Hokkaido Institute of Public Health, Hokkaido, Japan; #University of Munster, Munster, Germany; **US Department of Agriculture, Clay Center, Nebraska, USA;
Figure 3. Evolution model for Escherichia coli O157:H7. Figure modified and updated from (1) to include the sequence type (ST) data showing subclones within clonal complexes. Some strains, whose position on the model remains to be determined, are shown with dashed lines.
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