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Volume 13, Number 2—February 2007
Research

Invasive Group B Streptococcal Infection in Infants, Malawi

Katherine J. Gray*Comments to Author , Sally L. Bennett†, Neil French*, Amos J. Phiri*, and Stephen M. Graham*†
Author affiliations: *Malawi-Liverpool–Wellcome Trust Programme of Clinical Tropical Research, Blantyre, Malawi; †College of Medicine, Blantyre, Malawi;

Main Article

Table

Characteristics of 57 case-patients with group B streptococcal infection overall and in relation to capsular serotype

Serotype
Clinical featuresTotal (%)Ia
(n = 12)Ib
(n = 3)Ll
(n = 4)Lll
(n = 32)V
(n = 1)Unknown
(n = 5)
Early onset disease*297231412
Male sex†15 (52)‡622401
Meningitis5 (17)111200
Probable meningitis4 (14)100300
Sepsis15 (52)511800
Pneumonia0 (0)
Undefined5 (17)
0
0
1
1
1
2
Low birthweight§¶5 (17)210200
Premature#**3 (10)
2
0
0
1
0
0
Late onset disease††285111803
Male sex‡‡13 (46)211900
Meningitis11 (39)200801
Probable meningitis1 (4)000100
Sepsis10 (36)110800
Pneumonia3 (11)101100
Undefined3 (11)
1
0
0
0
0
2
Low birthweight§§5 (18)201101
Premature¶¶4 (14)
2
0
1
1
0
0
Case fatality‡
Early onset disease11 (38)300800
Late onset disease8 (29)300401
Unknown3 (5)
0
0
1
1
0
1
Sensitivity, %
Penicillin100100100100100100100
Erythromycin79901006778078
Tetracycline417000011
Ceftriaxone100100100100100100100
Chloramphenicol819010010078077

*Illness onset between birth and day 6.
†Missing information on 3 cases.
‡Expressed as a proportion of total early or late onset cases.
§Weight at birth <2.5 kg.
¶Missing information on 2 cases.
#Delivery before 37 weeks of gestation.
**Missing information on 6 cases.
††Illness onset ≥7 d after delivery.
‡‡Missing information on 2 cases.
§§Missing information on 4 cases.
¶¶Missing information on 6 cases.

Main Article

Page created: June 29, 2010
Page updated: June 29, 2010
Page reviewed: June 29, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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