Emerging Infectious Disease ISSN: 1080-6059

Global Emergence of Trimethoprim/Sulfamethoxazole Resistance in Stenotrophomonas maltophilia Mediated by Acquisition of sul Genes

Mark A. Toleman*, Peter M. Bennett*, David M.C. Bennett*, Ronald N. Jones†, and Timothy R. Walsh*

Author affiliations: *School of Medicine at Cardiff University, Cardiff, Wales; †The JONES Group/JMI Laboratories, North Liberty, Iowa, USA;

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Figure 1

Schematic diagram of class 1 integrons from Stenotrophomonas maltophilia isolates. A), isolates 1893 and 9431. B) isolates 489, 9189, and 12221; C) isolates 3438 and 3444. Arrows depict direction of transcription, and shaded boxes represent gene cassettes found within the integron. The dark circles represent the 59-bp region immediately 5′ to the incorporated gene cassette.

Figure 1. Schematic diagram of class 1 integrons from Stenotrophomonas maltophilia isolates. A), isolates 1893 and 9431. B) isolates 489, 9189, and 12221; C) isolates 3438 and 3444. Arrows depict direction of transcription, and shaded boxes represent gene cassettes found within the integron. The dark circles represent the 59-bp region immediately 5′ to the incorporated gene cassette.

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