Emerging Infectious Disease ISSN: 1080-6059

Avian Influenza (H5N1) Virus in Waterfowl and Chickens, Central China

Zhengjun Yu*¹, Yunfeng Song*¹, Hongbo Zhou*, Xiaojuan Xu*, Qiaoyun Hu*, Haiya Wu*, Anding Zhang*, Yanjun Zhou*, Jianfeng Chen*, Hanbing Dan*, Qingping Luo*, Xiangmin Li*, Huanchun Chen*, and Meilin Jin*

Author affiliations: *Huazhong Agricultural University, Wuhan, People’s Republic of China;

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Figure 1

Survival times of mice infected with the 7 avian influenza virus (H5N1) isolates. Mice were intranasally inoculated with 106 50% egg infectious dose of viruses in a volume of 50 μL. A/widgeon/Hubei/EWHC/2004 (EWHC), A/chicken/Hubei/327/2004 (CKDW), and A/goose/Hubei/ZFE/2004 (GOZF) induced a 100% death rate within 4–13 days, A/chicken/Hubei/XFJ/2004 (CKXF) induced a 50% death rate, and A/duck/Hubei/XFY/2004 (DKXF), A/chicken/Hubei/TMJ/2004 (CKTM), and A/chicken/Hubei/JZJ/2004 (CKJZ) caused no clinical signs or death.

Figure 1. Survival times of mice infected with the 7 avian influenza virus (H5N1) isolates. Mice were intranasally inoculated with 10⁶ 50% egg infectious dose of viruses in a volume of 50 μL. A/widgeon/Hubei/EWHC/2004 (EWHC), A/chicken/Hubei/327/2004 (CKDW), and A/goose/Hubei/ZFE/2004 (GOZF) induced a 100% death rate within 4–13 days, A/chicken/Hubei/XFJ/2004 (CKXF) induced a 50% death rate, and A/duck/Hubei/XFY/2004 (DKXF), A/chicken/Hubei/TMJ/2004 (CKTM), and A/chicken/Hubei/JZJ/2004 (CKJZ) caused no clinical signs or death.

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¹Contributed equally to this article.

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