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Volume 13, Number 6—June 2007

Research

Minority-Variant pfcrt K76T Mutations and Chloroquine Resistance, Malawi

Jonathan J. Juliano*, Jesse J. Kwiek*, Kathryn Cappell*, Victor Mwapasa†, and Steven R Meshnick*Comments to Author 
Author affiliations: *University of North Carolina, Chapel Hill, North Carolina, USA; †University of Malawi, Blantyre, Malawi

Main Article

Table 1

Characteristics of patient samples*

Characteristic Value (range)
Age (y)
Total 21.9 (15–35)
MHP patients 23.7 (17–31)
MM patients 21.2 (15–35)
Parasite density (no. parasites/200 leukocytes)
Total 243.6 (4–2,202)
MHP patients 599.7 (4–2,202)
MM patients 83.3 (5–750)
Gravidity
Total 2.26 (1–9)
MHP patients 2.37 (1–3)
MM patients 2.21 (1–9)
Anemia (hemoglobin <11 g/dL)
Total 64/87 (73.6%)
MHP patients 21/27 (77.8%)
MM patients 43/60 (71.7%)
HIV status
Total† 38/58 (65.5%)
MHP patients 27/27 (100%)
MM patients 11/31 (35.5%)
Clinical symptoms‡
Fever 14/27 (51.8%)
Headache 18/27 (66.7%)
General body pain 13/27 (48.1%)
Preventive measures‡
Bed net use§ 6/19 (31.6%)

*MHP, Malaria and HIV in Pregnancy; MM, Mpemba and Madziabango.
†29 patients declined testing.
‡Data only available for MHP patients.
§No data available for 8 patients.

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