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Volume 13, Number 7—July 2007

Research

Ongoing Genome Reduction in Mycobacterium ulcerans

Simona Rondini*1, Michael Käser*1, Timothy Stinear†2, Michel Tessier‡, Cyrill Mangold‡, Gregor Dernick‡, Martin Naegeli*, Françoise Portaels§, Ulrich Certa‡, and Gerd Pluschke*Comments to Author 
Author affiliations: *Swiss Tropical Institute, Basel, Switzerland; †Institut Pasteur, Paris, France; ‡F. Hoffmann-La Roche Ltd., Basel, Switzerland; §Institute of Tropical Medicine, Antwerp, Belgium; 1These authors contributed equally to this work.; 2Current affiliation: Monash University, Melbourne, Victoria, Australia;

Main Article

Table

Features of the 15 distinct deletions identified in Mycobacterium ulcerans isolates*

RDDeletion no.Plasmid no.OriginSize of deletion, kbNo. CDSs and pseudogenes
11p8SU/FG11.114
22p34SU/FG6.6–6.84
33Ap58AU1/AU23.55
3Bp58SU/FG3.86
44p60, p61SU/FG1.8–2.42
55p88, p153, p360ME1/ME227.1–27.423
66p92JP/CH/ME1/ME219.724
77p100SU/FG15.313
88p124, p291ME1/ME252.8–53.150
99Ap144JP/CH18.115
9Bp144SU/FG25.420
1010p170ME1/ME28.2–8.710
1111p305JP/CH4.67
1212Ap315JP/CH53.150
12Bp315SU/FG35.4–35.532

*RD, region of difference; CDSs, coding sequences; SU, Suriname; FG, French Guiana; AU, Australia; ME, Mexico; JP, Japan; CH, China.

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