Volume 13, Number 7—July 2007
Synopsis
Thottapalayam Virus, a Prototype Shrewborne Hantavirus
Jin-Won Song*, Luck Ju Baek*, Connie S. Schmaljohn†, and Richard Yanagihara‡
Table 1
Susceptibility of small laboratory animals of various ages to fatal Thottapalayam virus meningoencephalitis*
| Host species | Age at injection, d | Illness onset, d | Mortality rate, % |
|---|---|---|---|
| Mus musculus | 1 | 7 | 100 |
| 5 | 7 | 100 | |
| 10 | 6 | 88 | |
| 14 | 6 | 94 | |
| 21 | 8 | 67 | |
| Meriones unguiculatus | 1 | 9 | 100 |
| 5 | 11 | 100 | |
| 11 | 7 | 80 | |
| 16 | 14 | 100 | |
| Peromyscus maniculatus | 4 | 11 | 100 |
| Monodelphis domestica | 30 | – | 0 |
*Animals of various ages were injected intracerebrally with 6,000 PFU of Thottapalayam virus strain VRC-66412 and examined daily for neurologic signs and death.
