Volume 13, Number 7—July 2007
Research
Virulence Characteristics of Klebsiella and Clinical Manifestations of K. pneumoniae Bloodstream Infections
Victor L. Yu*
, Dennis S. Hansen†, Wen Chien Ko‡, Asia Sagnimeni*, Keith P. Klugman§, Herman Goossens#, Marilyn M. Wagener*, Vicente J. Benedi**1, Meningeal Disease Surveillance in South Africa¶, and the International Klebsiella Study Group
, Dennis S. Hansen†, Wen Chien Ko‡, Asia Sagnimeni*, Keith P. Klugman§, Herman Goossens#, Marilyn M. Wagener*, Vicente J. Benedi**1, Meningeal Disease Surveillance in South Africa¶, and the International Klebsiella Study GroupTable 2
Strain source and virulence factors, Taiwan and South Africa*
| Infection type | K1 or K2 serotype, % | Mucoid phenotype, % | Aerobactin producer, % | Mouse mortality rate, %† |
|---|---|---|---|---|
| Community-acquired pneumonia | 49 (23/47) | 68 (32/47) | 66 (31/47) | 47 |
| Invasive syndrome | 54 (7/13) | 100 (13/13) | 85 (11/13) | 82 |
| Other community-acquired | 15 (8/55) | 38 (21/55) | 42 (23/55) | 36 |
| Hospital-acquired | 16 (6/38) | 18 (7/37) | 16 (6/38) | 7 |
*Note that strains from patients in Taiwan and South Africa with community-acquired pneumonia or the invasive syndrome (liver abscess, endophthalmitis, meningitis) were more likely to have the putative virulence factors than hospital-acquired strains. See Results for p values.
†2 mice were tested for each available strain.
