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Volume 13, Number 8—August 2007
Research

Infection with Scedosporium apiospermum and S. prolificans, Australia

Louise Cooley*†, Denis Spelman*, Karin Thursky‡, and Monica Slavin*‡Comments to Author 
Author affiliations: *Alfred Hospital, Prahran, Victoria, Australia; †Royal Hobart Hospital, Hobart, Tasmania, Australia; ‡Royal Melbourne Hospital, Parkville, Victoria, Australia;

Main Article

Table 2

Characteristics of 8 patients with invasive disease and Scedospoeium prolificans infections, Australia, 1997–2003*

Patient no.Primary diseaseTransplant typeNeutropenia within 30 dGVHDDate of first isolateDays
post transplantInitial symptomSite of 
isolatesOutcome following diagnosis
1ALLAllogeneic HSCTYesChronic extensiveAug 
2000>400Knee effusionBlood, 
synovium, cartilage, prostateDied d 21
2AMLAllogeneic HSCTNoChronic extensiveApr 
2001>500Pulmonary 
infiltrateBlood, sputum, BAL, lungDied d 5
3MMAllogeneic HSCTYesNoNov 
200028Ethmoid sinus infiltrateEthmoid sinus, vertebral disc, mycotic aneurysmAlive d 500
4NHLAllogeneic HSCTYesNoDec 
200010Neutropenic 
sepsisBloodDied before diagnosis
5AMLAllogeneic HSCTYesNoMar 
200310Neutropenic 
sepsisBlood, sputum, BAL, lung, skinDied d 1
6MMAllogeneic HSCTYesChronic extensiveNov 
2002120PneumoniaSputumDied d 1
7MDSNANoNANov 
2003NAMaxillary sinus infiltrateSputum, maxillary sinus, pericardium, myocardium, kidney, skin, 
lungDied d 14
8AMLNAYesNAMay 2002NACatheter-related sepsisChest wall, Hickman catheterAlive d 500

*GVHD, graft versus host disease; ALL, acute lymphoblastic leukemia; HSCT, hematopoietic stem cell transplantation; AML, acute myeloid leukemia; BAL, bronchoalveolar lavage; MM, multiple myeloma; NHL, non-Hodgkin lymphoma; MDS, myelodysplastic syndrome; NA, not applicable because patients did not undergo stem cell transplantation.

Main Article

Page created: June 30, 2010
Page updated: June 30, 2010
Page reviewed: June 30, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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