Emerging Infectious Disease ISSN: 1080-6059

Novel Human Rhinoviruses and Exacerbation of Asthma in Children¹

Nino Khetsuriani, Xiaoyan Lu, W. Gerald Teague, Neely Kazerouni², Larry J. Anderson, and Dean D. Erdman

Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (N. Khetsuriani, X. Lu, N. Kazerouni, L.J. Anderson, D.D. Erdman); Emory University School of Medicine, Atlanta (W.G. Teague);

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Figure

Phylogenetic tree of partial virus capsid protein 1 (VP1) amino acid sequences of human rhinoviruses (HRVs) identified in 29 HRV-positive pediatric asthma patients, March 2003–February 2004, Atlanta, Georgia, USA (designated *), previously published sequences of strains QPM (GenBank accession no. EF186077), C024-C026 (accession nos. EF582385–EF582387), and NAT001 and NAT045 (accession nos. EF077279–EF077280). HRV prototype strains designated 1A, 1B, 2-100. Human enterovirus (HEV) 68/HRV87 (designated 68/87) is included as outgroup. Tree construction and bootstrap values determined with PAUP* (11).

Figure. Phylogenetic tree of partial virus capsid protein 1 (VP1) amino acid sequences of human rhinoviruses (HRVs) identified in 29 HRV-positive pediatric asthma patients, March 2003–February 2004, Atlanta, Georgia, USA (designated *), previously published sequences of strains QPM (GenBank accession no. EF186077), C024-C026 (accession nos. EF582385–EF582387), and NAT001 and NAT045 (accession nos. EF077279–EF077280). HRV prototype strains designated 1A, 1B, 2-100. Human enterovirus (HEV) 68/HRV87 (designated 68/87) is included as outgroup. Tree construction and bootstrap values determined with PAUP* (11).

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¹Part of the information in this article was presented at the International Conference of the American Thoracic Society, May 16–21, 2008, Toronto, Ontario, Canada.

²Current affilation: California Department of Public Health, Richmond, California, USA.

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