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Volume 14, Number 12—December 2008

Letter

Human Salmonella Infection Yielding CTX-M β-Lactamase, United States

Maria Sjölund-KarlssonComments to Author , Jennifer Yam, Jillian Schwenk, Kevin Joyce, Felicita Medalla, Ezra Barzilay, and Jean M. Whichard
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M. Sjölund, J. Yam, J. Schwenk, K. Joyce, F. Medalla, E. Barzilay, J.M. Whichard); Atlanta Research and Education Foundation, Atlanta (M. Sjölund, J. Yam, K. Joyce)

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Table

MIC values of antimicrobial drugs for the Salmonella ser. Typhimurium isolate and its Escherichia coli DH10B transformant

Antimicrobial agent MIC, mg/L
S. ser. Typhimurium E. coli DH10B transformant E. coli DH10B
Amikacin 1 1 1
Amoxicillin–clavulanic acid 32 16 4
Ampicillin >32 >32 4
Aztreonam 32 32 0.12
Cefepime 32 32 <0.06
Cefotaxime >64 >64 <0.06
Cefotaxime–clavulanic acid 0.25 0.12 <0.06
Cefoxitin 2 8 8
Cefquinome >32 >32 <0.06
Ceftazidime 8 8 0.5
Ceftazidime–clavulanic acid 0.5 0.25 0.12
Ceftiofur >8 >8 0.5
Ceftriaxone >64 >64 <0.25
Chloramphenicol >32 <2 <2
Ciprofloxacin <0.016 <0.016 <0.016
Gentamicin 4 <0.25 <0.25
Imipenem 0.5 0.25 0.25
Kanamycin >64 <8 <8
Nalidixic acid 4 1 1
Piperacillin-tazobactam >64 2 2
Streptomycin <32 >64 >64
Sulfisoxazole >256 <16 <16
Tetracycline >32 <4 <4
Trimethoprim-sulfamethoxazole >4 <0.12 <0.12

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