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Volume 14, Number 2—February 2008

Research

Severe Streptococcus pyogenes Infections, United Kingdom, 2003–2004

Theresa L. Lamagni*Comments to Author , Shona Neal*, Catherine Keshishian*, Neelam Alhaddad*, Robert C. George*, Georgia Duckworth*, Jaana Vuopio-Varkila†, and Androulla Efstratiou*
Author affiliations: *Health Protection Agency, London, United Kingdom; †National Public Health Institute, Helsinki, Finland;

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Table 1

Clinical manifestations of severe Streptococcus pyogenes infection, United Kingdom, 2003–2004

Manifestation All case-patients, 
no. (%)* Children <16 y of age, no. (%) Adults 16–60 y of age, no. (%) Adults >60 y of age, no. (%)
Skin/soft tissue infection 1,099 (42) 85 (27) 479 (39) 531 (50)
Cellulitis 881 (34) 59 (19) 362 (30) 457 (43)
Necrotizing fasciitis 136 (5) 4 (1) 87 (7) 45 (4)
Abscess 134 (5) 6 (2) 112 (9) 16 (2)
Erysipelas 24 (1) 2 (1) 9 (1) 13 (1)
Bacteremia with no defined focus 558 (21) 77 (24) 228 (19) 252 (24)
Respiratory tract infection 434 (17) 66 (21) 187 (15) 181 (17)
Pneumonia 309 (12) 27 (8) 139 (11) 143 (13)
Other lower respiratory tract infection 62 (2) 6 (2) 26 (2) 30 (3)
Pharyngitis/tonsillitis 51 (2) 26 (8) 16 (1) 9 (1)
Ear infection 22 (1) 8 (3) 9 (1) 5 (<1)
Epiglottitis 17 (1) 2 (1) 10 (1) 5 (<1)
Sinusitis 6 (<1) 4 (1) 0 2 (<1)
Septic arthritis 220 (8) 40 (13) 114 (9) 66 (6)
Puerperal sepsis 58 (2) 0 58 (5) 0
Acute abdominal infection† 49 (2) 5 (2) 31 (3) 12 (1)
Cardiac infection‡ 48 (2) 2 (1) 36 (3) 10 (1)
Meningitis 37 (1) 18 (6) 12 (1) 7 (1)
Total 2,611 (100) 318 (100) 1,225 (100) 1,064 (100)

*Includes patients without age information.
†Includes 14 patients with peritonitis, 1 with appendicitis, and 1 with pancreatitis.
‡Includes 42 patients with endocarditis, 4 with pericarditis, 1 with myocarditis, 1 with myocarditis and pericarditis.

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