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Volume 14, Number 2—February 2008

Research

Severe Streptococcus pyogenes Infections, United Kingdom, 2003–2004

Theresa L. Lamagni*Comments to Author , Shona Neal*, Catherine Keshishian*, Neelam Alhaddad*, Robert C. George*, Georgia Duckworth*, Jaana Vuopio-Varkila†, and Androulla Efstratiou*
Author affiliations: *Health Protection Agency, London, United Kingdom; †National Public Health Institute, Helsinki, Finland;

Main Article

Table 3

Potential predisposing factors for severe Streptococcus pyogenes infection, United Kingdom, 2003–2004

Factor All case-patients, no (%)* Children <16 y of age, no. (%) Adults 16–60 y of age, no. (%) Adults >60 y of age, no. (%)
Skin lesion/wound 719 (31) 63 (22) 298 (26) 358 (40)
Trauma 188 (8) 13 (5) 99 (9) 76 (9)
Chronic wound 161 (7) 0 39 (3) 122 (14)
Surgery 118 (5) 10 (4) 48 (4) 60 (7)
Injection drug use 459 (20) 0 459 (40) 0
Healthcare-associated infection 204 (9) 15 (5) 79 (7) 109 (12)
Malignancy 161 (7) 11 (4) 49 (4) 100 (11)
Diabetes 158 (7) 3 (1) 40 (4) 115 (13)
Alcoholism 88 (4) 0 67 (6) 21 (2)
Recent childbirth 86 (4) 0 86 (8) 0
Steroid use 77 (3) 3 (1) 35 (3) 39 (4)
Contact with person with S. pyogenes infection† 57 (4) 7 (4) 34 (5) 16 (2)
Nonsteroidal antiinflammatory drug use 49 (2) 3 (1) 18 (2) 28 (3)
Varicella 47 (2) 41 (14) 4 (<1) 2 (<1)
Cardiovascular disease 45 (2) 3 (1) 9 (1) 33 (4)
Upper respiratory tract infection 39 (2) 9 (3) 24 (2) 6 (1)
Renal impairment 31 (1) 2 (1) 19 (2) 10 (1)
Other reported risk factor‡ 112 (5) 30 (11) 41(4) 41 (5)
No risk factors reported
566 (25)
132 (46)
173 (15)
260 (29)
Total 2,305 (100) 284 (100) 1,135 (100) 884 (100)

*Includes patients without age information.
†Information available for 1,586 patients.
‡Noted for <30 patients.

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