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Volume 14, Number 2—February 2008

Research

Genetic Characterization of Feline Leukemia Virus from Florida Panthers

Meredith A. Brown*, Mark W. Cunningham†, Alfred L. Roca*‡§, Jennifer L. Troyer*§, Warren E. Johnson*, and Stephen J. O’Brien*Comments to Author 
Author affiliations: *National Cancer Institute, Frederick, Maryland, USA; †Florida Fish and Wildlife Conservation Commission, Gainesville, Florida, USA; ‡University of Illinois at Urbana-Champaign, Urbana, Illinois, USA; §SAIC-Frederick, Frederick, Maryland, USA;

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Appendix Figure 2

Top) Alignment of 1,794 bp of env nucleotide sequences corresponding to feline leukemia virus (FeLVA)-945 (AY662447) index sequence 154-1,869 bp. The shaded areas identify regions (indels) where panther FeLV (FeLV-Pco) sequences resemble those of FeLV-A, which rules out recombination with dissimilar endogenous FeLV sequences as represented in enFeLV-AGTT. Bottom) Panther sequences, with year of sampling (for example, FeLV-Pco-1058-03 was sampled in 2003); domestic cat subgroup A (FeLVA-945 and FeLVA-61E), recombinant (FeLVB-GA), and endogenous (enFeLV-AGTT) sequences are also shown. Matches to the reference sequence (Pco-1058-02) are indicated by a dot. Gaps are indicated by a dash.

Appendix Figure 2. Top) Alignment of 1,794 bp of env nucleotide sequences corresponding to feline leukemia virus (FeLVA)-945 (AY662447) index sequence 154-1,869 bp. The shaded areas identify regions (indels) where panther FeLV (FeLV-Pco) sequences resemble those of FeLV-A, which rules out recombination with dissimilar endogenous FeLV sequences as represented in enFeLV-AGTT. Bottom) Panther sequences, with year of sampling (for example, FeLV-Pco-1058-03 was sampled in 2003); domestic cat subgroup A (FeLVA-945 and FeLVA-61E), recombinant (FeLVB-GA), and endogenous (enFeLV-AGTT) sequences are also shown. Matches to the reference sequence (Pco-1058-02) are indicated by a dot. Gaps are indicated by a dash.

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