Volume 14, Number 3—March 2008
Dispatch
Hemagglutinating Encephalomyelitis Coronavirus Infection in Pigs, Argentina
Maria A. Quiroga*
, Javier Cappuccio*, Pablo Piñeyro*, Walter Basso*, Gastón Moré*, Mariana Kienast†, Sergio Schonfeld‡, José L. Cáncer‡, Sandra Arauz*, María E. Pintos*, Mariana Nanni†, Mariana Machuca*, Norio Hirano§, and Carlos J. Perfumo*
, Javier Cappuccio*, Pablo Piñeyro*, Walter Basso*, Gastón Moré*, Mariana Kienast†, Sergio Schonfeld‡, José L. Cáncer‡, Sandra Arauz*, María E. Pintos*, Mariana Nanni†, Mariana Machuca*, Norio Hirano§, and Carlos J. Perfumo*Table
Clinical signs and results of histopathologic examination, IHC testing, and RT-PCR from piglets affected by PHE-CoV*
| Organ | Days old (days with clinical signs) | IHC | RT-PCR | Histopathologic diagnosis |
|---|---|---|---|---|
| Brain stem | 6 (2) | + | + | Encephalitis |
| Brain stem | 8 (4) | + | + | Encephalitis |
| Trigeminal ganglion | 8 (4) | + | + | Focal ganglioneuritis |
| Brain stem | 8 (4) | ND | ND | Encephalitis |
| Spinal cord | 9 (5) | ND | + | Myelitis |
| Tonsil | 9 (5) | ND | ND | Necrotizing tonsilitis |
| Brain stem | 9 (5) | ND | ND | Meningoencephalitis |
| Medulla oblongata | 11(6) | + | + | Meningoencephalitis |
*IHC, immunohistochemical; RT-PCR, reverse transcription–PCR; PHE-CoV, porcine hemagluttinating encephalomyelitis coronavirus; ND, not done; +, positive.
