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Volume 14, Number 3—March 2008

Research

Mycobacterium ulcerans Disease, Peru

Humberto Guerra*, Juan Carlos Palomino†, Eduardo Falconí*‡, Francisco Bravo*, Ninoska Donaires*, Eric Van Marck§, and Françoise Portaels†Comments to Author 
Author affiliations: *Universidad Peruana Cayetano Heredia, Lima, Perú; †Institute of Tropical Medicine, Antwerp, Belgium; ‡Instituto Nacional de Salud del Perú, Lima, Perú; §University of Antwerp, Antwerp, Belgium;

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Table 2

Diagnostic laboratory studies on patients with Buruli ulcer, Peru*

Patient no. ITM no. AFB in smear (ZN) Histopathologic changes AFB in histologic sections IS2404 PCR Culture
1 None Positive Necrosis of fat Positive ND ND
2 96–0729 Positive Necrosis of fat Positive Positive Contaminated
3 01–0720 Positive Necrosis of fat Positive Positive Negative
4 02–1536 Positive Necrosis of fat Positive Positive Contaminated
5 02–1877 Negative (only 1 AFB seen) Necrosis of fat + granulomatous infiltrate Positive Positive Negative
6 04–0872 Positive Necrosis of fat Positive Positive Negative
7 05–2249
05–2411 Positive Necrosis of fat + inflammation Positive Positive Negative
8 None Positive Necrosis of fat + inflammation Positive Positive Negative

*ITM, Institute of Tropical Medicine; AFB, acid-fast bacilli; ZN, Ziehl-Neelsen staining; ND, not done.

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