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Volume 14, Number 4—April 2008
Dispatch

Human Mycobacterium bovis Infection and Bovine Tuberculosis Outbreak, Michigan, 1994–2007

Melinda J. Wilkins*Comments to Author , Joshua Meyerson†, Paul C. Bartlett‡, Susan L. Spieldenner*, Dale E. Berry*, Laura B. Mosher*, John B. Kaneene‡, Barbara Robinson-Dunn§, Mary Grace Stobierski*, and Matthew L. Boulton¶
Author affiliations: *Michigan Department of Community Health, Lansing, Michigan, USA; †Health Department of Northwest Michigan, Charlevoix, Michigan, USA; ‡Michigan State University, East Lansing, Michigan, USA; §Beaumont Hospital, Royal Oak, Michigan, USA; ¶University of Michigan, Ann Arbor, Michigan, USA;

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Table 1

Nonepidemiologically linked human Mycobacterium bovis spoligotyping and MIRU typing results for 9 available human specimens, Michigan*

Country of birth Site Year collected International spoligotype† MIRU type Spoligotypes
USA Cervical LN 1997 SB1210 Not available ▫▪▫▪▫▫▪▪▫▫▫▫▪▪▪▫▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▫▫▫▫▫
USA Spine 1997 SB0131 Not available ▪▪▫▪▫▪▪▪▫▪▫▪▪▪▪▫▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▫▫▫▫▫
Mexico Abd abscess 1998 SB0140 232224152322 ▪▪▫▪▪▫▪▫▫▫▫▫▪▪▪▫▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▫▫▫▫▫
Mexico Sputum 1998 SB1210 Not available ▫▪▫▪▫▫▪▪▫▫▫▫▪▪▪▫▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▫▫▫▫▫
Bosnia Cervical LN 2000 SB1215 232314353312 ▪▪▫▪▪▪▪▫▫▫▫▫▪▫▪▫▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▫▫▫▫▫
Mexico Sputum 2003 SB0121 232314223322 ▪▪▫▪▪▪▪▪▫▪▪▪▪▪▪▫▪▪▪▪▫▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▫▫▫▫▫
USA Cervical LN 2003 SB0121 232324252322 ▪▪▫▪▪▪▪▪▫▪▪▪▪▪▪▫▪▪▪▪▫▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▫▫▫▫▫
Mexico Cervical LN 2005 SB1216 232124233222 ▫▫▫▪▪▪▪▪▫▪▫▪▪▪▪▫▪▪▪▪▪▪▪▪▪▪▪▫▫▫▪▪▪▪▪▪▪▪▫▫▫▫▫
Mexico Cervical LN 2007 SB0140 231224243322 ▪▪▫▪▪▫▪▫▫▫▫▫▪▪▪▫▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▪▫▫▫▫▫

*MIRU, mycobacterial interspersed repeat units (6); LN, lymph node; Abd, abdominal.
†International Spoligotype Database, available from www.mbovis.org (7).

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References
  1. Enarson  DA, Rieder  HL, Meslin  FX, Cosivi  O. The importance of Mycobacterium bovis to the tuberculosis epidemic in humans. In: Thoen CO, Steel JH, editors. Mycobacterium bovis: infection in animals and humans. Ames (IA): Iowa State University Press; 2006. p. xxii–xxv.
  2. Wigle  WD, Ashley  MJ, Killough  EM, Cosens  M. Bovine tuberculosis in humans in Ontario: the epidemiologic features of 31 active cases occurring between 1964 and 1970. Am Rev Respir Dis. 1972;106:52834.PubMedGoogle Scholar
  3. Dankner  WM, Waecker  NJ, Essey  MA, Moser  K, Thompson  M, Davis  CE. Mycobacterium bovis infections in San Diego: a clinicoepidemiologic study of 73 patients and a historical review of a forgotten pathogen. Medicine (Baltimore). 1993;72:137. DOIPubMedGoogle Scholar
  4. Centers for Disease Control and Prevention. Human tuberculosis caused by Mycobacterium bovis—New York City, 2001–2004. MMWR Morb Mortal Wkly Rep. 2005;54:6058.PubMedGoogle Scholar
  5. Wilkins  MJ, Bartlett  PC, Frawley  B, O’Brien  DJ, Miller  CE, Boulton  ML. Mycobacterium bovis (bovine TB) exposure as a recreational risk for hunters: results of a Michigan Hunter Survey, 2001. Int J Tuberc Lung Dis. 2003;7:10019.PubMedGoogle Scholar
  6. Cowan  LS, Mosher  L, Diem  L, Massey  JP, Crawford  JT. Variable-number tandem repeat typing of Mycobacterium tuberculosis isolates with low copy numbers of IS6110 by using mycobacterial interspersed repetitive units. J Clin Microbiol. 2002;40:1592602. DOIPubMedGoogle Scholar
  7. Mycobacterium bovis international database [cited 2007 Mar 14]. Available from http://www.mbovis.org
  8. Yang  Z, Barnes  PF, Chaves  F, Eisenach  KD, Weis  SE, Bates  JH, Diversity of DNA fingerprints of Mycobacterium tuberculosis isolates in the United States. J Clin Microbiol. 1998;36:10037.PubMedGoogle Scholar
  9. Cowan  LS, Diem  L, Brake  MC, Crawford  JT. Transfer of a Mycobacterium tuberculosis genotyping method, spoligotyping, from a reverse line-blot hybridization, membrane-based assay to the Luminex multianalyte profiling system. J Clin Microbiol. 2004;42:4747. DOIPubMedGoogle Scholar
  10. Kwara  A, Schiro  R, Cowan  LS, Hyslop  NE, Wiser  MF, Harrison  SR, Evaluation of the epidemiologic utility of secondary typing methods for differentiation of Mycobacterium tuberculosis isolates. J Clin Microbiol. 2003;41:26835. DOIPubMedGoogle Scholar
  11. National  TB. Controllers Association/CDC Advisory Group on Tuberculosis Genotyping. Guide to the application of genotyping to tuberculosis prevention and control. Atlanta: Centers for Disease Control and Prevention; June 2004 [cited 2007 Mar 14]. Available from http://www.cdc.gov/nchstp/tb/genotyping/toc.htm

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