Volume 14, Number 4—April 2008
Dispatch
Single Nucleotide Polymorphism Typing of Bacillus anthracis from Sverdlovsk Tissue
Richard T. Okinaka*†, Melinda Henrie*, Karen K. Hill*, KristinS. Lowery‡, Matthew Van Ert†, Talima Pearson†, James Schupp†, Leo Kenefic†, Jodi Beaudry†, Steven A. Hofstadler‡, Paul J. Jackson*§, and Paul Keim*†¶
Table
Canonical single nucleotide polymorphism (canSNP) typing and a new pagA SNP from Sverdlovsk 7.RA93.15.15 (spleen)* View Actual Table
| Isolate | Country of origin | Lineage/group (10) | canSNP, A.Br.007 | canSNP, A.Br.008 | canSNP, A.Br.009 | SNP, pagA 981 |
|---|---|---|---|---|---|---|
| A1055 | C.Br.A055 | T | T | A | –pXO1 | |
| KrugerB | B.Br.KrugerB | T | T | A | A | |
| CNEVA.9066 | B.Br.CNEVA | T | T | A | A | |
| Ames | A.Br.Ames | T | T | A | A | |
| Sterne | A.Br.Ames | T | T | A | A | |
| Australia94 | A.Br.Aust94 | T | T | A | A | |
| Vollum | A.Br.Vollum | C | T | A | A | |
| (Branch point) | A.Br.008/009 | T | G | A | ||
| Sv7,RA93.15.15 (spleen) | A.Br.008/009 | T | G | A | T | |
| Sv31.RA93.39.3 | T | |||||
| Sv40.RA93.40.5 | T | |||||
| Sv25.RA93.031 | T | |||||
| Sv1.RA93.42.1 | T | |||||
| Sv33.RA93.20.5 | T | |||||
| Sv21.RA93.38.4 | T | |||||
| Western North America | A.Br.WNA | T | G | G | A | |
| A0362 | Norway | A.Br.008/009 | T | G | A | T |
| A0417 | Hungary | A.Br.008/009 | T | G | A | T |
| A0324 | Slovakia | A.Br.008/009 | T | G | A | T |
| A0293 | Italy | A.Br.008/009 | T | G | A | A |
| A0463 | Pakistan | A.Br.008/009 | T | G | A | A |
| A0149 | Turkey | A.Br.008/009 | T | G | A | A |
| A0264 | Turkey | A.Br.008/009 | T | G | A | A |
| A0032 | China | A.Br.008/009 | T | G | A | A |
| A0033 | China | A.Br.008/009 | T | G | A | A |
| A0241 | Turkey | A.Br.008/009 | T | G | A | A |
| A0245 | Turkey | A.Br.008/009 | T | G | A | A |
| A0463 | Pakistan | A.Br.008/009 | T | G | A | A |
*This table illustrates 2 canSNPs that distinguish the subgroup/branch point A.Br.008/009 from the Western North American (WNA) sublineage. The table also depicts the status of the pagA 981 SNP in 7 of 12 Sverdlovsk samples and several other key isolates. Black shading, WNA lineage; gray shading, subgroup A.Br.008/009.
