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Volume 14, Number 4—April 2008

Research

Clonal Population of Flucytosine-Resistant Candida tropicalis from Blood Cultures, Paris, France

Marie Desnos-Ollivier*, Stéphane Bretagne*†, Claire Bernède*‡, Vincent Robert§, Dorothée Raoux*, Elisabeth Chachaty¶, Elisabeth Forget#, Claire Lacroix**, Françoise Dromer*Comments to Author , and the YEASTS group
Author affiliations: *Institut Pasteur, Paris, France; †Hôpital Henri Mondor–Assistance Publique Hôpitaux de Paris, Créteil, France; ‡Institut Pasteur Institut National de la Santé et de la Recherche Médicale Unité 657, Paris, France; §Centraal Bureau voor Schimmelcultures, Utrecht, the Netherlands; ¶Institut Gustave-Roussy, Villejuif, France; #Hôpital Beaujon, Clichy, France; **Hôpital Saint Louis, Paris, France;

Main Article

Table 3

Distribution of the polymorphic microsatellites markers (PMM) profiles among 130 Candida tropicalis isolates, according to their susceptibility to flucytosine (5FC)*

Allelic association
Total no. isolates
(N = 130) No. isolate types
URA3 PMM CT14 PMM S5FC (n = 85) R5FC clone (n = 29) Other R5FC (n = 16)
172/172 142/148 3 3
172/172 148/154 2 2
172/174 142/148 3 2 1
172/174 148/148 1 1
172/174 148/154 1 1
172/176 142/148 5 4 1
174/174 142/148 5 3 2
174/174 148/148 1 1
174/174 148/151 1 1
174/174 148/154 6 6
174/174 151/154 1 1
174/174 154/154 1 1
174/176 142/148 6 6
174/176 148/151 1 1
174/176 151/151 3 3
174/178 142/148 8 5 3
174/178 145/151 1 1
174/178 148/148 5 5
174/178 148/151 2 1 1
176/176 142/148 11 10 1
176/176 148/148 3 3
176/176 148/151 4 4
176/176 151/151 1 1
176/178 142/148 3 3
176/178 145/151 1 1
176/178 148/148 1 1
176/178 148/151 5 5
176/178 148/157 1 1
176/180 151/151 1 1
178/178 142/148 3 2 1
178/178 145/151 6 3 3
178/178 148/151 33 4 29
178/178 151/151 1 1

*S subscript, susceptible; R subscript, resistant.

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1The YEASTS group is composed of (in alphabetical order by city): Claire Bouges-Michel (Hôpital Avicenne, Bobigny), Isabelle Poilane (Hôpital Jean Verdier, Bondy), Marie-Elisabeth Bougnoux, Jean Dunand (Hôpital Ambroise Paré, Boulogne), Guy Galeazzi (Hôpital Louis Mourier, Colombes), Stéphane Bretagne, Françoise Botterel (Hôpital Henri Mondor, Créteil), Nathalie Fauchet (Centre Hospitalier Intercommunal de Créteil, Créteil), Elisabeth Forget (Hôpital Beaujon, Clichy), Françoise Botterel, Christine Bonnal (Hôpital du Kremlin Bicêtre), Odile Eloy (Hôpital Mignot, Le Chesnay), Christine Lawrence (Hôpital Raymond Poincaré, Garches), Marie-Françoise David, Liliana Mihaila (Hôpital Paul Brousse, Villejuif), Elisabeth Chachaty, Olivier Adam (Institut Gustave Roussy, Villejuif), and in Paris: Christian Chochillon (Hôpital Bichat), André Paugam, Marie-Thérèse Baixench (Hôpital Cochin), Muriel Cornet (Hôpital de l’Hôtel Dieu), Marie-Christine Escande (Institut Curie), Svetlana Challier, Marie-Elisabeth Bougnoux (Hôpital Necker), Eric Dannaoui (Hôpital Européen Georges Pompidou), Annick Datry, Houria Laklache, Bader Lmimouni, Sophie Brun (Hôpital de la Pitié-Salpétrière), Jean-Louis Poirot (Hôpital Saint Antoine), Claire Lacroix (Hôpital Saint Louis), Didier Moissenet (Hôpital Trousseau), Michel Develoux (Hôpital Tenon), and Stéphane Bonacorsi (Hôpital Robert Debré).

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