Appendix Figure 1. Sensitivity of the ELISA typing test. A) ARQ/ARQ genotype. Fifteen experimental ovine bovine spongiform encephalopathy (BSE) animals from a first passage and 10 from a second passage were tested by using the typing ELISA, in at least 3 independent experiments. For some animals, different regions of the central nervous system were tested (animals SB1, 359, 397, 7704, and 7705). SC, spinal cord. BS, brain stem; FC, frontal cortex; PC, parietal cortex; OC, occipital cortex. B) ARR/ARR genotype. Seven experimental ovine BSE animals from a first passage were tested by using the typing ELISA, in at least 4 independent experiments.