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Volume 14, Number 4—April 2008

Research

Hemorrhagic Fever with Renal Syndrome Caused by 2 Lineages of Dobrava Hantavirus, Russia1

Boris Klempa*†2, Evgeniy A. Tkachenko‡2, Tamara K. Dzagurova‡, Yulia V. Yunicheva‡, Vyacheslav G. Morozov‡, Natalia M. Okulova‡, Galina P. Slyusareva‡, Aleksey Smirnov‡, and Detlev H. Kruger*Comments to Author 

Author affiliations: *Charité School of Medicine, Berlin, Germany; †Slovak Academy of Sciences, Bratislava, Slovakia; ‡Russian Academy of Medical Sciences, Moscow, Russia;

Main Article

Table 2

Clinical signs for 126 patients with Dobrava-Belgrade–associated
 hemorrhagic fever with renal syndrome, Lipetsk (2001–02) and Sochi (2000–2006) regions, Russia*

Selected criteria Region, %
Sochi, n = 18 Lipetsk, n = 108
Average duration of fever, d 7.1 5.4
Abdominal pain 89 46
Vision disturbance 12 1
Vomiting 72 27
Nausea 89 44
Diarrhea 50 11
Hyperemia of the face 72 29
Hemorrhagic sclerae 50 2
Hypertension 6 34
Liver enlargement 83 23
Oliguria (<500 mL) 77 35
Anuria (<200 mL) 39 8
Increased blood urea and creatinine 77 81
Death 5.6 0.9

*Boldface indicates statistically significant differences between groups. Comparison of binomial population proportions analysis implemented in Statlets (NWP Associates, Inc.; www.mrs.umn.edu/~sungurea/statlets/statlets.htm) indicates that the null hypothesis that the 2 proportions are equal could be rejected at significance level of 5.0%.

Main Article

1This work is dedicated to the memory of our friend and colleague Milan Labuda, who died in August 2007.

2These authors contributed equally to this article.

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