Volume 14, Number 4—April 2008
Research
Hemorrhagic Fever with Renal Syndrome Caused by 2 Lineages of Dobrava Hantavirus, Russia1
Boris Klempa*†2, Evgeniy A. Tkachenko‡2, Tamara K. Dzagurova‡, Yulia V. Yunicheva‡, Vyacheslav G. Morozov‡, Natalia M. Okulova‡, Galina P. Slyusareva‡, Aleksey Smirnov‡, and Detlev H. Kruger*
Table 2
Clinical signs for 126 patients with Dobrava-Belgrade–associated hemorrhagic fever with renal syndrome, Lipetsk (2001–02) and Sochi (2000–2006) regions, Russia*
| Selected criteria | Region, % |
|
|---|---|---|
| Sochi, n = 18 | Lipetsk, n = 108 | |
| Average duration of fever, d | 7.1 | 5.4 |
| Abdominal pain | 89 | 46 |
| Vision disturbance | 12 | 1 |
| Vomiting | 72 | 27 |
| Nausea | 89 | 44 |
| Diarrhea | 50 | 11 |
| Hyperemia of the face | 72 | 29 |
| Hemorrhagic sclerae | 50 | 2 |
| Hypertension | 6 | 34 |
| Liver enlargement | 83 | 23 |
| Oliguria (<500 mL) | 77 | 35 |
| Anuria (<200 mL) | 39 | 8 |
| Increased blood urea and creatinine | 77 | 81 |
| Death | 5.6 | 0.9 |
*Boldface indicates statistically significant differences between groups. Comparison of binomial population proportions analysis implemented in Statlets (NWP Associates, Inc.; www.mrs.umn.edu/~sungurea/statlets/statlets.htm) indicates that the null hypothesis that the 2 proportions are equal could be rejected at significance level of 5.0%.
1This work is dedicated to the memory of our friend and colleague Milan Labuda, who died in August 2007.
