Volume 14, Number 4—April 2008
Research
Hemorrhagic Fever with Renal Syndrome Caused by 2 Lineages of Dobrava Hantavirus, Russia1
Boris Klempa*†2, Evgeniy A. Tkachenko‡2, Tamara K. Dzagurova‡, Yulia V. Yunicheva‡, Vyacheslav G. Morozov‡, Natalia M. Okulova‡, Galina P. Slyusareva‡, Aleksey Smirnov‡, and Detlev H. Kruger*
Table 4
Complete nucleotide and amino acid sequence identities of the Sochi/Ap and Lipetsk/Aa strains of Dobrava-Belgrade virus compared with currently available cell culture isolates and most related virus sequences of rodent and human origin*
| Virus isolates | Sochi/Ap |
Lipetsk/Aa |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| S segment |
M segment |
S segment |
M segment |
||||||||
| nt | aa | nt | aa | nt | aa | nt | aa | ||||
| Sochi/Ap | – | – | – | – | 86.6 | 96.7 | 79.7 | 91.3 | |||
| Lipetsk/Aa | 86.6 | 96.7 | 79.7 | 91.3 | – | – | – | – | |||
| SK/Aa | 84.8 | 97.4 | 78.6 | 90.4 | 89.9 | 98.8 | 87.2 | 97.0 | |||
| Slo/Af | 87.8 | 97.6 | 79.3 | 93.3 | 88.5 | 96.7 | 82.7 | 94.0 | |||
| AP/Af19 | 87.6 | 97.9 | 79.6 | 93.3 | 88.2 | 97.4 | 82.5 | 94.1 | |||
| Saa/160V | 84.4 | 96.2 | 78.3 | 90.2 | 87.5 | 96.0 | 86.3 | 96.2 | |||
| Kurkino/53Aa/98 | 86.6 | 96.7 | NA | NA | 98.8 | 99.5 | NA | NA | |||
| Ap–1/Goryachiy Klyuch† | 96.8 | 98.8 | NA | NA | 87.3 | 96.5 | NA | NA | |||
| P–s1223/Krasnodar (patient)† | 98.7 | 99.4 | NA | NA | 86.5 | 96.4 | NA | NA | |||
*NA, not available.
†Values calculated from partial sequences available in GenBank (1,637 bp for Ap–1/Goryachiy Klyuch and 1,196 bp for P–s1223/Krasnodar).
1This work is dedicated to the memory of our friend and colleague Milan Labuda, who died in August 2007.
