Emerging Infectious Disease ISSN: 1080-6059

Cryptococcus neoformans Strains and Infection in Apparently Immunocompetent Patients, China

Jianghan Chen*, Ashok Varma†, Mara R. Diaz‡, Anastasia P. Litvintseva§, Kurt K. Wollenberg†, and Kyung J. Kwon-Chung†

Author affiliations: *Shanghai Changzheng Hospital, Shanghai, People’s Republic of China; †National Institutes of Health, Bethesda, Maryland, USA; ‡University of Miami, Miami, Florida, USA; §Duke University Medical Center, Durham, North Carolina, USA;

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Figure 4

Genetic relationship of multilocus sequence typing (MLST) genotypes among 94 isolates of Cryptococcus neoformans serotype A (88 strains from Litvintseva et al. [10]) and 6 representative Chinese strains) visualized by the neighbor-joining dendrogram. Numbers on each branch indicate the bootstrap values >50%, based on 500 replicates. Vertical lines represent strains with identical genotypes. Arrows indicate MLST results for Chinese strains.

Figure 4. Genetic relationship of multilocus sequence typing (MLST) genotypes among 94 isolates of Cryptococcus neoformans serotype A (88 strains from Litvintseva et al. [10]) and 6 representative Chinese strains) visualized by the neighbor-joining dendrogram. Numbers on each branch indicate the bootstrap values >50%, based on 500 replicates. Vertical lines represent strains with identical genotypes. Arrows indicate MLST results for Chinese strains.

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