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Volume 14, Number 8—August 2008


Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Adult Mute Swans

Donata Kalthoff*, Angele Breithaupt*, Jens P. Teifke*, Anja Globig*, Timm Harder*, Thomas C. Mettenleiter*, and Martin Beer*Comments to Author 
Author affiliations: *Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany;

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Table 2

Viral shedding among mute swans with preexisting antibodies*

Individual serologically positive Viral excretion, no. days shedding replication competent virus (DPI) Genome detection, no. days with positive PCR results (DPI) Peak titer log10/mL swab (DPI) Minimum Ct value (DPI)
No. 1 (contact) 1 (3) 0 7 (3-9) 6 (3-8) 1.75 (3) 0 32.12 (4) 31.65 (4)
No. 7 4 (2–5) 1 (4) 8 (1–8) 6 (3–7, 9) 2.63 (4) 1.75 (4) 26.44 (5) 29.49 (4)

*H5-specific real-time reverse transcription–PCR (RT-PCR) results of swab samples from swans. DPI, days postinoculation; Ct value, cycle threshold of the real-time RT-PCR; OS, oropharyngeal swab; CS, cloacal swab.

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