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Volume 15, Number 1—January 2009


Human Infection with Highly Pathogenic Avian Influenza Virus (H5N1) in Northern Vietnam, 2004–2005

Nguyen Duc Hien, Nguyen Hong Ha, Nguyen Tuong Van, Nguyen Thi Minh Ha, Trinh Thi Minh Lien, Nguyen Quoc Thai, Van Dinh Trang, Takuro ShimboComments to Author , Yoshimitsu Takahashi, Yasuyuki Kato, Akihiko Kawana, Samu Akita, and Koichiro Kudo
Author affiliations: National Institute of Infectious and Tropical Diseases, Hanoi, Vietnam (N.D. Hien, N.H. Ha, N.T. Van, N.T.M. Ha, T.T.M. Lien, N.Q. Thai, V.D. Trang); International Medical Center of Japan, Tokyo, Japan (T. Shimbo, Y. Takahashi, Y. Kato, A. Kawana, S. Akita, K. Kudo)

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Table 1

Characteristics of 29 patients infected with highly pathogenic avian influenza virus (H5N1), northern Vietnam, 2004–2005*

Characteristic Value
Age, y, mean ± SD 35.1 ± 14.4
M:F sex (%) 15:14 (52:48)
High-risk exposure, no. (%)†
Poultry 19 (65.5)
Sick poultry 12 (41.4)
Family infected with H5N1 virus subtype 6 (20.7)
Sick poultry or person 15 (51.7)
Hospitalization after disease onset, median, d (IQR) 6 (4–8)
Hospital stay, median, d (IQR) 14 (9–17)
Treated with oseltamivir, no. (%) 25 (86.2)
Began treatment with oseltamivir after disease onset, median, d (IQR) 7 (5–10)
Treated with methylprednisolone, no. (%) 15 (51.7)
Died, no. (%) 7(24.1)

*IQR, interquartile range.
†Poultry, a history of exposure to sick or healthy poultry; sick poultry or person, a history of exposure to sick poultry or a family infected with avian influenza (H5N1).

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