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Volume 15, Number 12—December 2009

CME ACTIVITY

Community-associated Methicillin-Resistant Staphylococcus aureus in Outpatients, United States, 1999–2006

Eili Klein, David L. Smith, and Ramanan LaxminarayanComments to Author 
Author affiliations: Princeton University, Princeton, New Jersey, USA (E. Klein, R. Laxminarayan); University of Florida, Gainesville, Florida, USA (D.L. Smith); Resources for the Future, Washington, DC, USA (E. Klein, R. Laxminarayan)

Main Article

Table

Frequency of MRSA in hospitals, by unit, United States, 1999–2006*

Unit % Patients (95% confidence interval)
1999 2000 2001 2002 2003 2004 2005 2006†
Outpatient
All MRSA 26.8 
(26.3–27.3) 29.4 
(29.0–29.9) 33.4 
(33.0–33.9) 35.7 
(35.3–36.2) 40.7 
(40.2–41.2) 47.7 
(47.3–48.1) 52.7 
(52.3–53.1) 52.4 
(52.0–52.9)
HA-MRSA 23.2 
(23.0–23.5) 25.1 
(24.9–25.4) 28.2 
(28.0–28.5) 28.4 
(28.2–28.7) 29.3 
(29.0–29.5) 28.4 
(28.2–28.7) 24.1 
(23.8–24.3) 24.2 
(24.0–24.5)
Blood 2.7 2.8 4.0 3.7 3.1 2.8 2.1 1.9
Lungs 4.7 5.3 6.5 5.5 5.4 4.2 3.5 2.9
Skin 9.3 10.6 10.1 11.6 13.8 15.5 14.2 15.5
Other source 6.4 6.5 7.6 7.7 7.0 6.0 4.2 4.0
CA-MRSA 3.6 
(3.5–3.7) 4.3 
(4.2–4.4) 5.2 
(5.1–5.4) 7.3 
(7.1–7.5) 11.4 
(11.3–11.6) 19.3 
(19.1–19.5) 28.7 
(28.4–28.9) 28.2 
(28.0–28.5)
Blood 0.3 0.3 0.6 0.7 0.8 0.8 0.9 0.8
Lungs 0.4 0.5 0.9 0.9 0.7 0.6 0.8 0.7
Skin 2.3 3.0 2.9 4.8 9.0 16.6 25.3 25.4
Other source
0.5
0.5
0.8
0.9
1.0
1.3
1.6
1.4
Inpatient
All MRSA 46.7 
(46.2–47.2) 47.6 
(47.2–48.1) 50.0 
(49.6–50.4) 52.2 
(51.8–52.6) 54.9 
(54.6–55.3) 58.3 
(57.9–58.6) 59.5 
(59.2–59.9) 58.5
(58.0–58.9)
HA-MRSA 43.4 
(43.0–43.9) 43.2
(42.8–43.6) 44.1
(43.7–44.5) 43.9 
(43.5–44.3) 44.1
(43.7–44.5) 41.9 
(41.6–42.3) 38.5 
(38.2–38.9) 38.7 
(38.3–39.1)
Blood 7.1 7.2 7.5 7.5 7.5 7.0 6.2 6.3
Lungs 21.4 19.9 19.2 18.5 17.6 16.5 14.7 14.5
Skin 9.3 10.5 11.4 12.0 12.9 13.1 13.0 13.1
Other source 5.6 5.6 6.0 5.9 6.1 5.3 4.5 4.7
CA-MRSA 3.3 
(3.1–3.4) 4.5 
(4.3–4.6) 5.8
(5.6–6.0) 8.4 
(8.2–8.6) 10.9 
(10.6–11.1) 16.3
(16.1–16.6) 21.0 
(20.7–21.3) 19.8
(19.4–20.1)
Blood 0.6 0.7 1.0 1.2 1.2 1.7 2.1 2.0
Lungs 1.2 1.6 2.1 2.3 2.1 2.6 3.3 3.8
Skin 1.1 1.7 2.1 4.0 6.6 10.9 14.4 12.8
Other source 0.4 0.5 0.7 0.9 1.0 1.2 1.3 1.2

*MRSA, methicillin-resistant Staphylococcus aureus; HA-MRSA, hospital-associated MRSA; CA-MRSA, community-associated MRSA.
†Data through October only. Data for blood, lungs, skin, and other source refer to the percentage of each source tested that was estimated to be CA-MRSA or HA-MRSA.

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