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Volume 15, Number 3—March 2009

Research

Sources of Hepatitis E Virus Genotype 3 in the Netherlands

Saskia A. RutjesComments to Author , Willemijn J. Lodder, Froukje Lodder-Verschoor, Harold H.J.L. van den Berg, Harry Vennema, Erwin Duizer, Marion Koopmans, and Ana Maria de Roda Husman
Author affiliations: National Institute for Public Health and the Environment, Bilthoven, the Netherlands

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Table 2

Nucleotide identities between environmental and human HEV strains that circulated during 2004–2006, the Netherlands*

Cluster Nucleotide identities between environmental HEV strains†
Nucleotide identities between human and environmental HEV strains†
Nucleotide identities between human HEV strains†
No. strains compared Minimal, % Maximal, % No. strains compared Minimal, % Maximal, % No. strains compared Minimal, % Maximal, %
3a 6 96.0 99.3 7 96.6 99.3 1
3c 16 88.5 100 28 87.2 100 12 88.2 100
3e 3 91.2 96.6 5 92.6 97.3 2 93.3 97.3
3f 20 87.2 97.3 21 88.5 93.9 1

*HEV, hepatitis E virus; –, no identities (1 human HEV sequence was present).
†Based on a 148-nt sequence of open reading frame 2 (nt 6322–6469 of strain M73218).

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