Volume 15, Number 3—March 2009
CME ACTIVITY
Clinical Risk Factors for Severe Clostridium difficile–associated Disease
Timothy J. Henrich
, Douglas Krakower, Asaf Bitton, and Deborah S. Yokoe
, Douglas Krakower, Asaf Bitton, and Deborah S. YokoeTable 4
Binary logistic regression model to identify variables independently associated with severe CDAD, 336 patients*
| Variable | OR | 95% CI |
|---|---|---|
| Age >70 y | 3.35† | 1.48–7.57 |
| Female | 0.93 | 0.42–2.03 |
| Antimicrobial-drug use | 1.76 | 0.60–5.21 |
| Malignancy | 0.73 | 0.33–1.65 |
| Immunocompromised | 0.38 | 0.07–1.96 |
| Small bowel obstruction or ileus | 3.06‡ | 1.00–9.39 |
| Abnormal abdominal CT scan | 13.54† | 5.72–32.07 |
| Prior hospitalization | 1.39 | 0.61–3.18 |
| SNF/rehabilitation stay | 1.11 | 0.46–2.68 |
*CDAD, Clostridium difficile–associated disease; OR, odds ratio; CI, confidence interval; CT, computed tomography; SNF, skilled-nursing facility. Constant included in analysis.
†p<0.05.
‡p = 0.05.
