Medscape, LLC is pleased to provide online continuing medical education (CME) for this journal article, allowing clinicians the opportunity to earn CME credit. This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of Medscape, LLC and Emerging Infectious Diseases. Medscape, LLC is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Medscape, LLC designates this educational activity for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity. All other clinicians completing this activity will be issued a certificate of participation. To participate in this journal CME activity: (1) review the learning objectives and author disclosures; (2) study the education content; (3) take the post-test and/or complete the evaluation at http://www.medscape.com/cme/eid; (4) view/print certificate.

Learning Objectives

Upon completion of this activity, participants will be able to:

• Identify the criteria used to define severe Clostridium difficile–associated disease (CDAD) in the current study
• Specify the prevalence of severe CDAD in the current study
• Identify the clinical risk factors for severe CDAD
• List the laboratory risk factors for severe CDAD

CME Editor

Lynne Stockton, Technical Writer-Editor, Emerging Infectious Diseases. Disclosure: Lynne Stockton has disclosed no relevant financial relationships.

CME Author

Charles P. Vega, MD, Associate Professor; Residency Director, Department of Family Medicine, University of California, Irvine. Disclosure: Charles P. Vega, MD, has disclosed that he has served as an advisor or consultant to Novartis, Inc.

Authors

Disclosures: Timothy J. Henrich, MD; Douglas Krakower, MD; Asaf Bitton, MD; and Deborah S. Yokoe, MD, MPH, have disclosed no relevant financial relationships.