Medscape, LLC is pleased to provide online continuing medical education (CME) for this journal article, allowing clinicians the opportunity to earn CME credit. This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of Medscape, LLC and Emerging Infectious Diseases. Medscape, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Medscape, LLC designates this educational activity for a maximum of 0.5 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity. All other clinicians completing this activity will be issued a certificate of participation. To participate in this journal CME activity: (1) review the learning objectives and author disclosures; (2) study the education content; (3) take the post-test and/or complete the evaluation at http://www.medscape.com/cme/eid; (4) view/print certificate.

Learning Objectives

Upon completion of this activity, participants will be able to:

• Describe the impact of HIV infection on malaria infection
• Identify different levels of severity of malaria infection
• Describe the presentation of severe malaria in patients infected with HIV-1 in one region in Zambia
• Compare the risk for severe malaria in relation to CD4 count in patients infected with HIV-1

CME Editor

Karen L. Foster, Writer-Editor, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA; copyeditor, Emerging Infectious Diseases. Disclosure: Karen L. Foster has disclosed no relevant financial relationships.

CME Author

Désirée Lie, MD, MSEd, Clinical Professor, Family Medicine, University of California, Orange, California, USA; Director, Division of Faculty Development, UCI Medical Center, Orange. Disclosure: Désirée Lie, MD, MSEd, has disclosed no relevant financial relationships.

Authors

Disclosures: Victor Chalwe, MD, MSc; Jean-Pierre Van geertruyden, MD, PhD; Doreen Mukwamataba, RN; Joris Menten, MSc; John Kamalamba, MD; Modest Mulenga, MD, PhD; and Umberto D'Alessandro, MD, PhD, have disclosed no relevant financial relationships.